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Do your eyes hurt?

The eyes can hurt in many different ways. A person may feel that their eyes are sore, aching, burning, or stinging, or that they have an object or other foreign body stuck in them. Home remedies cannot cure serious eye conditions or infections, such as a fungal infection or uveitis. If a person's eye pain is severe, persistent, or accompanied by other symptoms such as pus or sensitivity to light they should see a doctor. Any loss of vision is also a reason to seek medical advice. People at risk of developing eye disease or complications should also see a doctor if they experience any eye pain. This includes people with diabetes, high blood pressure, and conditions that weaken the immune system. Newborn babies can develop serious conditions as a result of eye infections. Parents and caregivers should take infants with puffy eyelids, red eyes, or eye discharge to a doctor right away. More severe eye pain may occur due to migraine, a scratched cornea, or an infection. If possible, a person should speak to a doctor about their symptoms.

(Credits: www.medicalnewstoday.com)

Novel neurotransmitters effectively cross the blood-brain barrier

The blood-brain barrier poses a crucial challenge for doctors hoping to deliver drugs and other therapeutic substances directly to the brain. A new study from researchers at Tufts University in Boston, MA, describes a way of getting medication safely across the blood-brain barrier. The researchers found that certain neurotransmitters can help lipid-based nanoparticles pass through the blood-brain barrier and into the brain. The blood-brain barrier consists of a blood vessel lining of endothelial cells that keeps foreign molecules from escaping from the blood vessels and entering the brain fluid where they could affect neurons and other brain cells. The barrier is highly selective about the non-native molecules it allows into the brain, and that includes therapeutic substances. While small molecule or macromolecule drugs have the potential to treat brain tumors, infections, neurogenerative disorders, and stroke, the presence of the blood-brain barrier makes it difficult for doctors to administer such therapies. Scientists have attempted various workarounds, and none have proven sufficiently safe or effective. Direct injection of compounds into the brain, as well as efforts to force ‘leaks’ through the barrier, carry risks, such as neurotoxicity, infection, and tissue damage. (Credits: www.medicalnewstoday.com)