Alzheimer's disease is the most common form of dementia, affecting approximately 50 million people worldwide. In the race to gain a better understanding of the drivers behind Alzheimer's disease, one research team looks to the link between the brain, the gut, and the liver. The researchers decided to start taking liver function into account — in the context of Alzheimer's disease — because of the organ's role in the body's metabolic processes. In this study, blood biomarkers, reflecting liver function, were related to brain imaging and [cerebrospinal fluid] markers associated with Alzheimer's. No stone can be left unturned in our attempt to understand the disease and to identify viable therapeutic targets.", says Andrew Saykin. In the future, the current findings plus other related investigations may help perfect a more personalized approach to treating Alzheimer's, as precision medicine keeps on gaining ground.