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Resveratrol is a plant compound which has grabbed a great deal of medical world’s attention. The reason behind this is the medicinal aid it provides which include protective effects against stroke, heart failure, and hypertension, among other heart conditions. Recent study on mice has proven outcomes which helps reduce blood pressure also. Resveratrol is abundantly found in Blueberries, red grapes, red wine, peanuts etc. and is famous for its antioxidant properties while cardiovascular effects still remain unclear. To find out more about its properties in lowering blood pressure, researchers conducted study on a group of wild mice. Researchers measured the rodent blood pressure with implanted telemetry probes and monitored this for 15 days. Meanwhile, they were fed either with resveratrol rich diet or a normal diet. By the end of the study, results showed a drop of 20 millimeters of mercury in the blood pressure of mice that had consumed resveratrol. Another finding was that by oxidising the protein PKG1a, resveratrol also relaxed blood vessels of the rodents. Prof. Avkiran explains how the findings will be of help to humans, “This study reveals the surprising way in which resveratrol works and opens up the possibility of new blood pressure drugs which work in a similar way. The findings bring us a step closer to tackling this silent killer which puts people at risk of having a devastating stroke or heart attack.

(www.medicalnewstoday.com)

Scientists have been aware of the negative impacts of improper sleep rates since a long time. The impacts are short term as well as long term in humans. It mainly affects an individual cardiovascular system. But improper sleep effects on circulation have always remained unclear. Through some new studies, scientists have uncovered some potential mechanisms. Researchers from University of Colorado Boulder are looking into how circulation is affected by promoting the build-up of fatty deposits in the arteries (atherogenesis) due to lack of sleep, which in turn leads to stroke or heart attack. This study proposes a new potential mechanism through which sleep influences heart health and overall physiology, says senior author Prof. Christopher DeSouza. After the study, results showed that patients who received less than the optimum 7 hours of sleep had their blood levels of three key circulating miRNAs that were 40-60% lower than the participants who received 7-8 hours of sleep. These three key circulating miRNAs - miR- 125A, miR-126, and miR-146 lead to suppression of expression of proinflammatory proteins. Prof. DeSouza says,they are like cellular brakes, so if beneficial microRNAs are lacking, that can have a big impact on the health of the cell and explains how lack of sleep can affect our health in due course of time.
(www.medicalnewstoday.com)