According to the latest estimates from the Centers for Disease Control and Prevention (CDC), more than 12% of adults in the United States have tried e- cigarettes at least once in their lives, and almost 4% of U.S. adults use e- cigarettes on a regular basis. New research examines the effects of a few puffs of nicotine-free electronic cigarettes on endothelial function, a measure of blood vessel health. Alessandra Caporale, a postdoctoral researcher in the Laboratory for Structural, Physiologic, and Functional Imaging at the University of Pennsylvania in Philadelphia, is the lead author of the study. Caporale and her colleagues looked at the short term effects of vaping. They asked 31 healthy, nonsmoking adults with an average age of 24 years to take an MRI scan before and after using a nicotine-free e-cigarette. The e- cigarettes contained propylene glycol and glycerol with tobacco flavoring but did not provide any nicotine. For the study, the participants took 16 puffs, which lasted 3 seconds each. The scans revealed reduced blood flow in the femoral artery — the main artery that delivers blood to the thigh and leg. The team also noted reduced reactive hyperemia. Based on these measures, the researchers concluded that "inhaling nicotine-free electronic cigarette aerosol transiently impacted endothelial function in healthy nonsmokers." Beyond the harmful effects of nicotine, we've shown that vaping has a sudden, immediate effect on the body's vascular function and could potentially lead to long term harmful consequences.", says Prof. Felix W. Wehrli, Ph.D. (Credit: www.medicalnewstoday.com)
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