Coffee is one beverage considered as a life saver by many around the world. It is well known for brightening up a day, increasing productivity and as a mood booster. Coffee is often consumed at the start of a day, midday, in the evening and after dinner for better digestion. Its aroma, taste, role as a stimulant etc. have brought it up as one of the world’s most popular beverages. Statistics report that in the year 2018-19 alone, 26.5 million 60-kilogram bags of coffee have been consumed by U.S population and it is rising per year. Along with coffee’s positive properties of increasing focus, brain health and life span, it also aids slowing down prostate cancer. But, like any other food item, no matter however nutritious it is, coffee also has its adverse impacts when a certain limit is crossed. Previous studies have helped scientists draw the conclusion that people containing the genetic variant CYP1A2 in their body are less likely to develop easy metabolism of caffeine. Hence, caffeine causes an increased risk of high blood pressure which will lead to higher chances of getting cardiovascular diseases. In the new study, the investigators wanted to determine how much coffee would increase the cardiovascular risk of people with and without this genetic variant. Results of the study showed that, even though individuals without CYP1A2 genetic variant were able to break down caffeine 4 times faster than individuals without it, that had nothing to do with cardiovascular diseases. But, the amount of coffee consumption did have an impact on the same. "In order to maintain a healthy heart and a healthy blood pressure, people must limit their coffees to fewer than six cups a day — based on our data six was the tipping point where caffeine started to negatively affect cardiovascular risk.", says Prof. Elina Hyppönen.
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